Penurunan Kadar Glukosa Darah Mencit (Mus Musculus) yang Diinduksi Hiperglikemia oleh Ekstrak Etanol Daun Sirsak (Annona muricata L.)

Hyperglycemia is one of the diabetes mellitus characteristics. Soursop leaves (Annona muricata L.) has been used traditionally to reduce blood glucose level and clinically need be proven. The aim this study was observe effect ethanol extract soursop (EDS) on levels hyperglycemia mice (Mus musculus). This an experimental with a pre-post test control group design. Thirty as animal models induced by alloxan 150mg/kg b.w, respectively. Treatment EDS given for 14 days variation doses; 200 mg/Kg 300 400 bw. Fasting measured before after treatment glucocheck. Data were analyzed ANOVA Duncan further tests evaluate while difference in treament paired t-test. result showed that significantly reduced (p < 0.05). bw dose strongest reducing levels, followed b.w doses. In conclusion, potential develop agent mellitus.